Gianfranco Pasut
Professor of Pharmaceutical Technology, University of Padova
Short Bio
ORCID 0000-0002-8754-0899
PubMed
ResearchID I-5944-2012
ResearchGate
Our research focuses on drug delivery approaches for different pharmacological active molecules (proteins, drugs, genetic materials, etc.). The main studied systems are polymer conjugates, antibody-drug conjugates and liposomes.
Short Bio
ORCID 0000-0002-8754-0899
PubMed
ResearchID I-5944-2012
ResearchGate
A valuable approach to increase the potential of biotech drugs by reducing body clearance, degradation and immunogenicity.
To precisely deliver a potent drug to target cells.
To reduce drug side effects and promote tumour accumulation by EPR effect and surface modification of liposomes with targeting agents
Recent publications, available positions, etc.
Canato E, Grigoletto A, Zanotto I, Tedeschini T, Campara B, Quaglio G, Toffoli G, Mandracchia D, Dinarello A, Tiso N, Argenton F, Sayaf K, Guido M, Gabbia D, De Martin S, Pasut G. Anti-HER2 Super Stealth Immunoliposomes for Targeted-Chemotherapy. Adv Healthc Mater. 2023;XXXX. doi: 10.1002/adhm.202301650
Grigoletto A, Marotti V, Tedeschini T, Campara B, Marigo I, Ingangi V, Pasut G. Improving the Therapeutic Potential of G-CSF through Compact Circular PEGylation Based on Orthogonal Conjugations. Biomacromol. 2023;XXXX. doi: 10.1021/acs.biomac.3c00543
Saggioro M, D'Agostino S, Gallo A, Crotti S, D'Aronco S, Corallo D, Veltri G, Martinez G, Grigoletto A, Tolomeo AM, Tafuro G, Agostini M, Aveic S, Serafin V, Semenzato A, Pasut G, Pozzobon M. A rhabdomyosarcoma hydrogel model to unveil cell-extracellular matrix interactions. Biomater Sci. 2021;10(1):124-137. doi: 10.1039/d1bm00929j.
Bigini P, Gobbi M, Bonati M, Clavenna A, Zucchetti M, Garattini S, Pasut G. The role and the impact of polyethylene glycol on the anaphylactic reactions to the COVID-19 nano-vaccines. Nat Nanotech. 2021;16(11):1169-1171. doi: 10.1038/s41565-021-01001-3.
Polymer-Protein Conjugates:
From Pegylation and Beyond
1st Edition - October 30, 2019
Editors: Gianfranco Pasut, Samuel Zalipsky
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