Offline Website Builder1. Tedeschini T, Campara B, Grigoletto A, Zanotto I, Cannella L, Gabbia D, Matsuno Y, Suzuki A, Yoshioka H, Armirotti A, De Martin S, Pasut G. Optimization of a pendant-shaped PEGylated linker for antibody-drug conjugates. J Control Release. 2024;375:74-89. doi: 10.1016/j.jconrel.2024.08.049
2. Paolino D, d'Avanzo N, Canato E, Ciriolo L, Grigoletto A, Cristiano MC, Mancuso A, Celia C, Pasut G, Fresta M. Improved anti-breast cancer activity by doxorubicin-loaded super stealth liposomes. Biomater Sci. 2024;12(15):3933-3946. doi: 10.1039/d4bm00478g.
3. Grigoletto A, Marotti V, Tedeschini T, Campara B, Marigo I, Ingangi V, Pasut G. Improving the Therapeutic Potential of G-CSF through Compact Circular PEGylation Based on Orthogonal Conjugations. Biomacromol. 2023;24:4229-4239. doi: 10.1021/acs.biomac.3c00543
4. Canato E, Grigoletto A, Zanotto I, Tedeschini T, Campara B, Quaglio G, Toffoli G, Mandracchia D, Dinarello A, Tiso N, Argenton F, Sayaf K, Guido M, Gabbia D, De Martin S, Pasut G. Anti-HER2 Super Stealth Immunoliposomes for Targeted-Chemotherapy. Adv Healthc Mater. 2023;12: e2301650. doi: 10.1002/adhm.202301650
5. Fongaro B, Campara B, Moscatiello GY, De Luigi A, Panzeri D, Sironi L, Bigini P, Carretta G, Miolo G, Pasut G, Polverino De Laureto P. Assessing the physicochemical stability and intracellular trafficking of mRNA-based COVID-19 vaccines. Int J Pharm. 2023;644:123319. doi: 10.1016/j.ijpharm.2023.123319
6. Pavan M, Fanti CD, Lucia AD, Canato E, Acquasaliente L, Sonvico F, Delgado J, Hicks A, Torrelles JB, Kulkarni V, Dwivedi V, Zanellato AM, Galesso D, Pasut G, Buttini F, Martinez-Sobrido L, Guarise C. Aerosolized sulfated hyaluronan derivatives prolong the survival of K18 ACE2 mice infected with a lethal dose of SARS-CoV-2. Eur J Pharm Sci. 2023;187:106489. doi: 10.1016/j.ejps.2023.106489.
7. Battista MR, Grigoletto A, Tedeschini T, Cellucci A, Colaceci F, Laufer R, Pasut G, Di Marco A. Efficacy of PEGylated ciliary neurotrophic factor superagonist variant in diet-induced obesity mice. PLoS One. 2022;17(3):e0265749. doi: 10.1371/journal.pone.0265749.
8. Dodd A, Natfji AA, Evangelinos A, Grigoletto A, Pasut G, Beards F, Renshall L, Osborn HMI, Greco F, Harris LK. Conjugation to PEG as a Strategy to Limit the Uptake of Drugs by the Placenta: Potential Applications for Drug Administration in Pregnancy. Mol Pharm. 2022;19(1):345-353. doi: 10.1021/acs.molpharmaceut.1c00498.
9. Saggioro M, D'Agostino S, Gallo A, Crotti S, D'Aronco S, Corallo D, Veltri G, Martinez G, Grigoletto A, Tolomeo AM, Tafuro G, Agostini M, Aveic S, Serafin V, Semenzato A, Pasut G, Pozzobon M. A rhabdomyosarcoma hydrogel model to unveil cell-extracellular matrix interactions. Biomater Sci. 2021;10(1):124-137. doi: 10.1039/d1bm00929j.
10. Bigini P, Gobbi M, Bonati M, Clavenna A, Zucchetti M, Garattini S, Pasut G. The role and the impact of polyethylene glycol on the anaphylactic reactions to the COVID-19 nano-vaccines. Nat Nanotech. 2021;16(11):1169-1171. doi: 10.1038/s41565-021-01001-3.
11. Tedeschini T, Campara B, Grigoletto A, Bellini M, Salvalaio M, Matsuno Y, Suzuki A, Yoshioka H, Pasut G. Polyethylene glycol-based linkers as hydrophilicity reservoir for antibody-drug conjugates. J Control Release. 2021;337:431-447. doi: 10.1016/j.jconrel.2021.07.041.
12. Grigoletto A, Martinez G, Gabbia D, Tedeschini T, Scaffidi M, De Martin S, Pasut G. Folic Acid-Targeted Paclitaxel-Polymer Conjugates Exert Selective Cytotoxicity and Modulate Invasiveness of Colon Cancer Cells. Pharmaceutics. 2021;13(7):929. doi: 10.3390/pharmaceutics13070929.
13. Dalla Pietà A, Carpanese D, Grigoletto A, Tosi A, Dalla Santa S, Pedersen GK, Christensen D, Meléndez-Alafort L, Barbieri V, De Benedictis P, Pasut G, Montagner IM, Rosato A. Hyaluronan is a natural and effective immunological adjuvant for protein-based vaccines. Cell Mol Immunol. 2021;18(5):1197-1210. doi: 10.1038/s41423-021-00667-y.
14. Delfino D, Mori G, Rivetti C, Grigoletto A, Bizzotto G, Cavozzi C, Malatesta M, Cavazzini D, Pasut G, Percudani R. Actin-Resistant DNase1L2 as a Potential Therapeutics for CF Lung Disease. Biomolecules. 2021;11(3):410. doi: 10.3390/biom11030410.
15. Grigoletto A, Tedeschini T, Canato E, Pasut G. The evolution of polymer conjugation and drug targeting for the delivery of proteins and bioactive molecules. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2020:e1689. doi: 10.1002/wnan.1689.
16. Maso K, Grigoletto A, Raccagni L, Bellini M, Marigo I, Ingangi V, Suzuki A, Hirai M, Kamiya M, Yoshioka H, Pasut G. Poly(L-glutamic acid)-co-poly(ethylene glycol) block copolymers for protein conjugation. J Control Release. 2020;324:228-237. doi: 10.1016/j.jconrel.2020.05.015.
17. Alajati A, D'Ambrosio M, Troiani M, Mosole S, Pellegrini L, Chen J, Revandkar A, Bolis M, Theurillat JP, Guccini I, Losa M, Calcinotto A, De Bernardis G, Pasquini E, D'Antuono R, Sharp A, Figueiredo I, Nava Rodrigues D, Welti J, Gil V, Yuan W, Vlajnic T, Bubendorf L, Chiorino G, Gnetti L, Torrano V, Carracedo A, Camplese L, Hirabayashi S, Canato E, Pasut G, Montopoli M, Rüschoff JH, Wild P, Moch H, De Bono J, Alimonti A. CDCP1 overexpression drives prostate cancer progression and can be targeted in vivo. J Clin Invest. 2020;130(5):2435-2450. doi: 10.1172/JCI131133.
18. Giacomini I, Ragazzi E, Pasut G, Montopoli M. The Pentose Phosphate Pathway and Its Involvement in Cisplatin Resistance. Int J Mol Sci. 2020;21(3):E937. doi: 10.3390/ijms21030937.
19. Cilurzo F, Cristiano MC, Da Pian M, Cianflone E, Quintieri L, Paolino D, Pasut G. Overcoming Cancer Cell Drug Resistance by a Folic Acid Targeted Polymeric Conjugate of Buthionine Sulfoximine. Anticancer Agents Med Chem. 2019;19(12):1513-1522. doi: 10.2174/1871520619666190626114641.
20. Maso K, Montagner IM, Grigoletto A, Schiavon O, Rosato A, Pasut G. A non-covalent antibody complex for the delivery of anti-cancer drugs. Eur J Pharm Biopharm. 2019;142:49-60. doi: 10.1016/j.ejpb.2019.06.012.
21. Catanzaro D, Nicolosi S, Cocetta V, Salvalaio M, Pagetta A, Ragazzi E, Montopoli M, Pasut G. Cisplatin liposome and 6-amino nicotinamide combination to overcome drug resistance in ovarian cancer cells. Oncotarget. 2018;9:16847-16860. doi: 10.18632/oncotarget.24708
22. Grigoletto A, Mero A, Yoshioka H, Schiavon O, Pasut G. Covalent immobilisation of transglutaminase: stability and applications in protein pegylation. J Drug Targeting. 2017;25:856-864. doi: 10.1080/1061186X.2017.1363211
23. Montagner IM, Merlo A, Carpanese D, Dalla Pietà A, Mero A, Grigoletto A, Loregian A, Renier D, Campisi M, Zanovello P, Pasut G, Rosato A. A site-selective hyaluronan-interferonα2a conjugate for the treatment of ovarian cancer. J Control Release. 2016;236:79-89. doi: 10.1016/j.jconrel.2016.06.033
24. Grigoletto A, Maso K, Mero A, Rosato A, Schiavon O, Pasut G. Drug and protein delivery by polymer conjugation. J Drug Deliv Sci Tech. 2016;32:132-141. doi: 10.1016/j.jddst.2015.08.006
25. Pasut G, Panisello A, Folch-Puy E, Lopez A, Castro-Benítez C, Calvo M, Carbonell T, García-Gil A, Adam R, Roselló-Catafau J. Polyethylene glycols: An effective strategy for limiting liver ischemia reperfusion injury. World J Gastroenterol. 2016;22(28):6501-8. doi: 10.3748/wjg.v22.i28.6501.
26. Mero A, Grigoletto A, Maso K, Yoshioka H, Rosato A, Pasut G. Site-selective enzymatic chemistry for polymer conjugation to protein lysine residues: pegylation of G-CSF at lysine-41. Pol Chem. 2016;7:6545-6553. doi: 10.1039/C6PY01616B
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